Downregulated PDIA3P1 lncRNA Impairs Trophoblast Phenotype by Regulating Snail and SFRP1 in PE

<div>SFRP1<sup>′</sup>s impact on trophoblast proliferation and migration. (a) Validation of cell proliferation viability in si-SFRP1-transfected HTR-8/SVneo and JAR cells using EdU assay. (b) CCK-8 assays determine the proliferation ability of HTR-8/SVneo cells cotransfected with si-PDIA3P1 and si-SFRP1. (c) Colony formation assays assessing viability of si-PDIA3P1- and si-SFRP1-cotransfected HTR-8/SVneo cells. (d) Proliferation ability of JAR cells cotransfected with si-PDIA3P1 and si-SFRP1 analyzed by CCK-8 assays. (e) Colony formation assays determining viability of si-PDIA3P1- and si-SFRP1-cotransfected JAR cells. (f) Transwell assays investigating changes in the migration abilities of si-PDIA3P1- and si-SFRP1-cotransfected HTR-8/SVneo cells. 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Analytical Cellular Pathology

fig5

Figure 5

Figure 5: Downregulated PDIA3P1 lncRNA Impairs Trophoblast Phenotype by Regulating Snail and SFRP1 in PE 